Crackdown takes place in the fictional metropolis of Pacific City, whose three districts are divided among eight total islands. The city is controlled by three criminal organizations: Los Muertos (which means "The Dead" in Spanish), a street gang of drug dealers from Central America who runs "La Mugre" ("The Dirt"); The Volk (Russian for "The Wolf"), a militia group from Eastern Europe who dominates "The Den"; and the Shai-Gen Corporation, a formerly above-board, corrupt governing body from East Asia that rules "The Corridor".[4] Normally, a police organization called the Peacekeepers kept the city under control; their forces, however, were overwhelmed by the sudden rise in crime. The city, therefore, sought additional help from "the Agency", an organization that, in addition to outfitting and supporting Peacekeepers, has used advanced surgical and cybernetic technology to create supersoldiers known as "Agents". The Agency is based out of a former resort hotel on an island in the very centre of the city. The player takes on the role of one of their Agents, and is tasked with systematically bringing down all three organized gangs, while keeping both the populace and Peacekeepers safe.[4] The Agent's actions are continuously monitored by the Agency, and its Director (voiced by Michael McConnohie) provides continuous reports to him of his progress.
Throughout the game, the player roams Pacific City, systematically eliminating the leaders of the three gangs. Upon defeating the gangs' Kingpins and generals, the Agent must put down a final riot by the remaining gang members in the area which after completion will cause that city to be almost crime free. Once all three gangs are fully exterminated, in the closing cutscene of the game, the Director reveals to the Agent that there was an ulterior motive for the Agency's actions: the Agency had secretly empowered the three gangs in the first place to instill fear in Pacific City's residents, thus creating a need for the Agency to control the city, and acceptance in the populace when they did take over. The Agency Director's comments suggest that the Agency was merely using Pacific City as a test and will replicate this plan in other cities across the globe to create a New World Order.[5]