Destroy All Humans! Path of the Furon has over 30-story missions, 20 side quests, and multiplayer modes. As with previous games, most story missions can be played in a non-linear order. Creative director Jon Knoles said that the side quests are related to the story, creative and "epic". Knoles added that the achievements are tied to statistic tracking in the game, and they are unique to the weapons and abilities found, allowing the player to experiment with different possibilities. For example, IGN noted that when the player takes the "Sunny" off of the Sunnywood sign they get a cutscene and one of the more creative achievements.[7][8] There are also challenges and mini-games that the player can return to repeatedly to better their score and collect more rewards. There are five new open-world locations based on Las Vegas ("Las Paradiso"), Hollywood ("Sunnywood"), Hong Kong ("Shen Long"), Paris ("Belleville"), and the home planet of the Furons itself, The 4th Ring of Furon.[9]