Each course is controlled by a spirit, each with an obsession — one loves money, one loves fast things, one loves friendliness, one loves strength, etc. They will set out guidelines for the course, such as collecting fruit to free a certain number of Egglings, finishing a course before time runs out, finding a certain number of coins or defeating — or not defeating — a certain number of enemies. By satisfying that spirit's requirements, players pass the course.
Yoshi can jump and stick out his tongue to eat fruit or enemies. After eating an enemy, Yoshi will produce a small puff of air instead of making eggs. The main feature of the game is the tilt mechanism. By moving the Game Boy Advance side to side, players tilt the world around Yoshi, causing enemies to roll around, swinging ships and pendulums, and bouncing items all over the place. An impassable wall will become a climbable slope, or a rolled-up carpet will become a long platform. Each environment requires players to master not only button presses but also tilt movements to progress.